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IBX2 is a crystallized myelin protein related to the disease mulitiple sclerosis. In multiple sclerosis, the immune system launches an attack against the myelin sheath surrounding nerve cells, causing them to misfire. According to the Multiple Sclerosis Foundation, up to 500,000 people in the United States have been diagnosed with the condition, which causes varying symptoms depending on the location and extent of the scarring of the myelin sheath. Common symptoms include fatigue, weakness, vertigo, numbness and vision problems.This protein - alphaB-crystallin - is not normally found in the brain, but develops in response to the injuries inflicted on nerve cells by multiple sclerosis. The nerve-cell injuries can cause people to suffer loss of motor control and even paralysis.



This protein shows to have tertiary structure due to it's three dimensional structure. Also containing alpha helices and beta pleated sheets.

image source: ncbi.nlm.nih.gov